Dewees Creek is one of the many deep water streams offering overnight anchorage between Winyah Bay and Charleston Harbor. The only disadvantage I can remember in regards to this haven is 100% marsh grass shores, which do not give the best of protection in really heavy weather.
I didn’t know about the “shark hole” (see below). That’s interesting!

We anchored recently at the Northern most spot shown above. Dolphins were swimming and diving all around for hours. It’s a nice spot.
On the way in, there’s a `hole’ about 90 feet deep. It’s known locally as `shark hole’.
Ron Widman

Click Here To View the South Carolina Cruisers’ Net Anchorage Directory Listing For The Dewees Creek Anchorages